megatomi.com - An Overview
megatomi.com - An Overview
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Our new Obvious+ tissue clearing procedure is the only real process that delipidates samples without having improve in morphology and with minimal impact on structural integrity.
Megatome is actually a vibrating microtome intended to part a wide number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform surface area profile, and also small tissue problems and knowledge decline.
Antibodies may take weeks to diffuse through only some millimeters of tissue, with a steep labeling gradient from area to Main.
Megatome is created for precision: the blade vibrates at a better frequency and larger amplitude variety than other microtomes, and incorporates a exclusive deflection Management system.
SE employs a rotational electric area to disperse hugely electromobile molecules (including antibodies or surfactant micelles) all through a porous sample with out damaging electrically billed constructions inside the tissue. This enables 2-four working day clearing of intact organs,
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them fully clear. This permits light penetration in the sample and guarantees the acquisition of superior-resolution, in-concentrate image facts.
Megatome is actually a novel microtome which allows for prime-precision sectioning of megatomi.com a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data reduction.
It’s time for you to enhance your microtome to Megatome. With correct substantial-frequency slicing for an unmatched selection of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
The SmartSPIM light-weight sheet microscope offers unparalleled resolution and acquisition pace in the course of intact tissue volumes, though its modular style and design permits you to enhance and personalize unique elements.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, defending specimens for a number of rounds of processing.
Leverage the Obvious+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to swiftly apparent and label full organs. Crucial highlights and capabilities include:
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